Open Fly - data licence and citations ===================================== The brain data in this folder is not Open Fly's code. It is derived from the FlyWire connectome, and it has its own licence. connectome.bin (and its connectome.bin.part.* parts) who connects to whom, and how strongly brain.bin neuron positions and classes, for the 3D view brain.json sensory and descending neurons, as indices LICENCE These files are licensed under Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0): https://creativecommons.org/licenses/by-nc/4.0/ Source: FlyWire public release 783, https://flywire.ai - Princeton University and collaborators. "FlyWire's public release data is made available under license CC BY-NC 4.0" (https://flywire.ai/guidelines). NON-COMMERCIAL. You may copy, share and adapt these files, with credit, for any purpose that is not commercial. Open Fly asks for no money and carries no ads for this reason. CHANGES MADE (tools/export_web_brain.py and open_fly/live.py) - Connectivity_783.parquet and Completeness_783.csv, as prepared from FlyWire 783 by Shiu et al. (signed synapse counts, where the sign comes from FlyWire's neurotransmitter predictions), were re-encoded as a binary compressed sparse row table (connectome.bin). - Positions and super classes from flyconnectome/flywire_annotations (Supplemental_file1_neuron_annotations.tsv) were re-encoded for the 3D view (brain.bin). - Descending neurons from the same annotations, and sensory neurons listed in Shiu et al.'s notebooks, were converted to indices. The descending neurons were dealt into the game's 39 action groups (brain.json). - For Cloudflare Pages, the large files are served gzip-compressed and split into parts. CITATIONS Following FlyWire's citation table, for the parts of the data used here: Dorkenwald et al. (2024). Neuronal wiring diagram of an adult brain. Nature 634, 124-138. https://doi.org/10.1038/s41586-024-07558-y Schlegel et al. (2024). Whole-brain annotation and multi-connectome cell typing of Drosophila. Nature 634, 139-152. https://doi.org/10.1038/s41586-024-07686-5 Zheng et al. (2018). A complete electron microscopy volume of the brain of adult Drosophila melanogaster. Cell 174, 730-743. https://doi.org/10.1016/j.cell.2018.06.019 Buhmann et al. (2021). Automatic detection of synaptic partners in a whole-brain Drosophila electron microscopy data set. Nature Methods 18, 771-774. https://doi.org/10.1038/s41592-021-01183-7 Heinrich et al. (2018). Synaptic cleft segmentation in non-isotropic volume electron microscopy of the complete Drosophila brain. MICCAI 2018, LNCS 11071, 317-325. https://doi.org/10.1007/978-3-030-00934-2_36 Eckstein, Bates et al. (2024). Neurotransmitter classification from electron microscopy images at synaptic sites in Drosophila melanogaster. Cell 187, 2574-2594. https://doi.org/10.1016/j.cell.2024.03.016 For the annotations (flywire_annotations v3): Matsliah, Yu et al. (2024). Neuronal parts list and wiring diagram for a visual system. Nature 634, 166-180. https://doi.org/10.1038/s41586-024-07981-1 Berg et al. (2025). Sexual dimorphism in the complete connectome of the Drosophila male central nervous system. bioRxiv. https://doi.org/10.1101/2025.10.09.680999 The brain model that runs on this data: Shiu et al. (2024). A Drosophila computational brain model reveals sensorimotor processing. Nature 634, 210-219. https://doi.org/10.1038/s41586-024-07763-9 Code: https://github.com/philshiu/Drosophila_brain_model, MIT License, Copyright (c) 2023 Philip Shiu and Nico Spiller.